Relative Biological Effectiveness of Alpha-Particle Emitters In Vivo at Low Doses
نویسندگان
چکیده
منابع مشابه
Basics of particle therapy II: relative biological effectiveness
In the previous review, the physical aspect of heavy particles, with a focus on the carbon beam was introduced. Particle beam therapy has many potential advantages for cancer treatment without increasing severe side effects in normal tissue, these kinds of radiation have different biologic characteristics and have advantages over using conventional photon beam radiation during treatment. The re...
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A radiation field is made up of a tangle of particle tracks, from the primary particle and secondary and higher generation electron interactions, well isolated at low doses and with multiple intersections in cell nuclei at high doses. Low dose effects in multicellular systems are therefore the sum of individual track structures. Until we can state with confidence the structure of a particle tra...
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The “Linear No Threshold” hypothesis, used in all radiation protection practices, assumes that all doses, no matter how low, increase risk. However, in human and other mammalian cells, low doses of low LET radiation such as gamma and X-rays induce an adaptive response that protects against both radiation-induced and spontaneous risk. An in vivo test of the hypothesis in mice showed that a 100-m...
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Background: The International Commission on Radiological Protection (ICRP) has attributed the same relative risk for X and gamma radiations of all energies. Several studies have proven that the biological effect of low energy photon is more than that of higher ones. The assessment of risks is important due to the wide use of low energy X-rays for mammography screening and other diagnostic appli...
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ژورنال
عنوان ژورنال: Radiation Research
سال: 1994
ISSN: 0033-7587
DOI: 10.2307/3578710